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kindly see the web page. More Bad News for Vytorin. The SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) trial compared Vytorin to placebo in about 1800 paients with aortic stenosis, a stiffening of one of the heart valves. As reported in several sources, including Forbes, the most recent study on Vytorin was not exactly positive.